NAVLE® Question of the day

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January 13, 2025
NAVLE

A horse presents with distal limb edema in all 4 limbs (as seen below), petechiae of the mucous membranes, depression, and a low-grade fever of 101.9°F/38.8°C (N = 99-101°F, 37.2-38.3°C). Multiple horses in the stable recently suffered from an upper respiratory infection of undiagnosed etiology.

Which type of immune reaction is most likely responsible for the vasculitis in this horse?