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A 9-year-old German shepherd is presented with unchecked bleeding from a cut on the gums above the right canine tooth. The owner relates that the dog has lost weight and had an episode of collapse 3 days ago, but he recovered.

On physical exam, the gums are pale with petechiae and ecchymotic hemorrhages. There is tachycardia and a palpable cranial abdominal mass.

A coagulation profile shows the following:

Thrombocytes= 82,533 per microliter..[N=200,000-900,000]
Buccal mucosal bleeding time (BMBT), increased
Activated partial thromboplastin time (aPTT), increased
Prothrombin time (PT), increased
Thrombin time (TT), increased
Fibrin degradation products (FDPs), increased

What disorder of coagulation best fits this pattern?



A -

Von Willebrand's disease


B -

Idiopathic thrombocytopenia


C -

Hepatic insufficiency


D -

Anticoagulant rodenticide toxicity


E -

Disseminated intravascular coagulation